Anxiety is one of the problems that might occur during the outbreak of a pandemic, which is usually caused due to chronic stress in people. This anxiety will have far more destructive effects on the body and the psyche of those people inside an environment where their freedom is taken from them (such as prisons or detention centers). The reason is that it is really difficult and sometimes impossible to follow health protocols in these environments, the fact which makes prisoners more likely to be infected in comparison with others. Moreover, in these environments, in addition to the stress caused by the disease, there are several other sources of stress which cause people to suffer from different types of anxiety. This study aims to scrutinize the factors which cause anxiety as well as the consequences of anxiety caused by the prevalence of a pandemic inside prisons. It also suggests ways to prevent, control and treat anxiety in prisoners.