Objective: Inter-organizational cooperation is considered as one of the strongest factors of value creation and among the most important business tool. Today ability to manage is considered a competitive advantage. Cooperation can be occurred in various stages of the value chain and in each of the sectors of research, product development, production, marketing, distribution and services after-sales. Methodology: The form of cooperation is in a spectral between two ranges "buy" and "merge-ownership". Piter Draker states that: "The biggest change in the way of business is the increase of communication growth based on partnership not based on ownership. Today inter-organizational cooperation is as one of the most important business management tool to improve the competitiveness of organizations, especially in complex and turbulent environments and ability in its effective management is considered a competitive advantage. Stimulus of companies to enter strategic alliances is to achieve a high level of success that achieving this level of success alone is not possible. Results: The current research is review and in terms of methodology is in the place of descriptive study. In this study, it is tried to provide a conceptual framework of inter-organizational cooperation by the method of library and literature of conducted studies and with a total look and all-round, cooperation models and factors affecting it as well as causes of communication between the organizations investigated. Conclusion: Currently circumstances and environment governing the activity of organizations formed in such a way that it can be said that continue of their existence is in relationship with each other. Perhaps, in the past, the image of some organizations was possible that only by relying on capacity, capability, financial resources, human and intelligence were able to survive. But on the horizon of time and in parallel with the evolution and development of organizations, the image is fainter and the need of relationships between the organizations is strengthened.
