Objective: The aim of this study is to predict the attitudes to pre-marital relations due to social support and sensation seekingin undergraduate students of Islamic Azad University of Karaj in the 2015 academic year. Methodology: For this purpose, 150 students were selected by random sampling. Data was collected by using of social protection by Philips, Zuckerman's Sensation Seeking and Kordlo's attitude-orientation about having pre-marital relations questionnaires and were analyzed by using the multiple regressions. Results: The findings of this research showed that there is a significant negative correlation(r= -0.61) between the attitudes to pre-marital relations and social support and a significant positive correlation(r=0.63) with sensation seeking. The attitudes to pre-marital relations has a significant positive correlation all components of social support (friends, others and family) and a significant negative correlation with all the components of sensation seeking (sensation seeking, experience seeking and adventure). Conclusion: Also, the predictive role of social support and sensation seeking was approved and among the components of social support, family factors and others and among the component of sensation seeking, experience and adventure-seeking could predict the attitudes to pre-marital relations (p<0.05).